Flex-T MHC tetramer 四聚體
Flex-T™ 是我們專為研究特定抗原 T細胞而設計的試劑家族，通過主要組織相容性複合物（MHC）四聚體實現。我們提供兩種不同的 Flex-T™。
UVX 單體為您提供了將任何感興趣的肽載入複合體結合位點的靈活性，方法是使用對紫外線敏感的肽，通過簡單的 ELISA 分析，可以監測肽交換的效率。
此外，我們也有提供預先載有與疾病相關或模型抗原肽的單體，例如：SARS-CoV-2 MHC 單體，包括核膜 (nuceloplasmid) 或棘突蛋白 （spike protein)。
BioLegend 的 Flex-T™ 試劑以單體形式提供，研究人員可以在準備就緒時構建其 MHC 四聚體複合物，並進行流式細胞術實驗，以檢測具有對感興趣抗原的受體的 T 細胞。
MHC 四聚體的應用 |
- 細胞治療研究： T 細胞表面受體 TCR 親和力的研究、抗體篩選研究、 T-Cell Receptor-Like Antibodies 篩選
- MHC免疫功能研究： 利用混合抗原表位片段鑒定 MHC 免疫功能
- 細胞分選： 特異性T細胞高效分選
- 抗原表位研究： 抗原表位短肽親和力的篩選
- 病毒逃逸研究： 病毒逃避免疫機制的研究
Flex-T™ 技術優勢 |
 |  |  |
| 實驗靈活性高 | 可搭配多色螢光組合 | 具有高通量篩選能力 |
 |  |  |
| 高專一性 | 容易操作好上手 | 性價比高 |
Flex-T™ 實驗流程 |
Flex-T™ 產品清單 |
Human Class I Biotinylated Monomer UV-Labile Peptide
| 品名 | 規格 | 貨號 | ||||||||||||
| Flex-T HLA-A*01:01 Monomer UVX | 50 μg | 280001 | ||||||||||||
| Flex-T HLA-A*02:01 Monomer UVX | 50 μg 200 μg | 280003 280004 |
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| Flex-T HLA-A*02:03 Monomer UVX | 50 μg | 280017 | ||||||||||||
| Flex-T HLA-A*03:01 Monomer UVX | 50 μg | 280005 | ||||||||||||
| Flex-T HLA-A*11:01 Monomer UVX | 50 μg | 280007 | ||||||||||||
| Flex-T HLA-A*24:02 Monomer UVX | 50 μg | 280019 | ||||||||||||
| Flex-T HLA-B*07:02 Monomer UVX | 50 μg | 280009 | ||||||||||||
| Flex-T HLA-B*08:01 Monomer UVX | 50 μg | 280011 | ||||||||||||
| Flex-T HLA-B*15:01 Monomer UVX | 50 μg | 280129 | ||||||||||||
| Flex-T HLA-C*04:01 Monomer UVX | 50 μg | 280015 | ||||||||||||
| Flex-T HLA-C*07:01 Monomer UVX | 50 μg | 280133 | ||||||||||||
| Flex-T HLA-C*07:02 Monomer UVX | 50 μg | 280131 | ||||||||||||
| Human Class I Biotinylated Monomer SARS-CoV-2 Fixed Peptide | ||||||||||||||
| 品名 | Peptide Region | 貨號 | ||||||||||||
| Flex-T Biotin HLA-A*01:01 SARS-CoV-2 Monomer (ATSRTLSYY) | SARS-CoV-2 Membrane Protein | 280087 | ||||||||||||
| Flex-T Biotin HLA-A*02:01 SARS-CoV-2 Monomer (TLACFVLAAV) | SARS-CoV-2 Membrane Protein | 280033 | ||||||||||||
| Flex-T Biotin HLA-A*03:01 SARS-CoV-2 Monomer (ATSRTLSYY) | SARS-CoV-2 Membrane Protein | 280089 | ||||||||||||
| Flex-T Biotin HLA-A*03:01 SARS-CoV-2 Monomer (ATSRTLSYYK) | SARS-CoV-2 Membrane Protein | 280115 | ||||||||||||
| Flex-T Biotin HLA-A*11:01 SARS-CoV-2 Monomer (ATSRTLSYY) | SARS-CoV-2 Membrane Protein | 280091 | ||||||||||||
| Flex-T Biotin HLA-A*11:01 SARS-CoV-2 Monomer (ATSRTLSYYK) | SARS-CoV-2 Membrane Protein | 280113 | ||||||||||||
| Flex-T Biotin HLA-A*02:01 SARS-CoV-2 Monomer (GMSRIGMEV) | SARS-CoV-2 Nucleocapsid | 280021 | ||||||||||||
| Flex-T Biotin HLA-A*02:01 SARS-CoV-2 Monomer (LLLDRLNQL) | SARS-CoV-2 Nucleocapsid | 280023 | ||||||||||||
| Flex-T Biotin HLA-A*03:01 SARS-CoV-2 Monomer (ATEGALNTPK) | SARS-CoV-2 Nucleocapsid | 280111 | ||||||||||||
| Flex-T Biotin HLA-A*03:01 SARS-CoV-2 Monomer (KTFPPTEPK) | SARS-CoV-2 Nucleocapsid | 280093 | ||||||||||||
| Flex-T Biotin HLA-A*11:01 SARS-CoV-2 Monomer (ATEGALNTPK) | SARS-CoV-2 Nucleocapsid | 280109 | ||||||||||||
| Flex-T Biotin HLA-A*11:01 SARS-CoV-2 Monomer (KTFPPTEPK) | SARS-CoV-2 Nucleocapsid | 280095 | ||||||||||||
| Flex-T Biotin HLA-B*07:02 SARS-CoV-2 Monomer (SPRWYFYYL) | SARS-CoV-2 Nucleocapsid | 280123 | ||||||||||||
| Flex-T Biotin HLA-A*01:01 SARS-CoV-2 Monomer (CTDDNALAY) | SARS-CoV-2 ORF1ab | 280085 | ||||||||||||
| Flex-T Biotin HLA-A*01:01 SARS-CoV-2 Monomer (PTDNYITTY) | SARS-CoV-2 ORF1ab | 280083 | ||||||||||||
| Flex-T Biotin HLA-A*01:01 SARS-CoV-2 Monomer (TTDPSFLGR) | SARS-CoV-2 ORF1ab | 280081 | ||||||||||||
| Flex-T Biotin HLA-A*02:01 SARS-CoV-2 Monomer (ALWEIQQVV) | SARS-CoV-2 ORF1ab | 280077 | ||||||||||||
| Flex-T Biotin HLA-A*02:01 SARS-CoV-2 Monomer (KLWAQCVQL) | SARS-CoV-2 ORF1ab | 280075 | ||||||||||||
| Flex-T Biotin HLA-A*03:01 SARS-CoV-2 Monomer (MVTNNTFTLK) | SARS-CoV-2 ORF1ab | 280101 | ||||||||||||
| Flex-T Biotin HLA-A*03:01 SARS-CoV-2 Monomer (VTDTPKGPK) | SARS-CoV-2 ORF1ab | 280107 | ||||||||||||
| Flex-T Biotin HLA-A*11:01 SARS-CoV-2 Monomer (MVTNNTFTLK) | SARS-CoV-2 ORF1ab | 280103 | ||||||||||||
| Flex-T Biotin HLA-A*11:01 SARS-CoV-2 Monomer (VTDTPKGPK) | SARS-CoV-2 ORF1ab | 280105 | ||||||||||||
| Flex-T Biotin HLA-A*24:02 SARS-CoV-2 Monomer (VYIGDPAQL) | SARS-CoV-2 ORF1ab | 280121 | ||||||||||||
| Flex-T Biotin HLA-B*07:02 SARS-CoV-2 Monomer (IPRRNVATL) | SARS-CoV-2 ORF1ab | 280127 | ||||||||||||
| Flex-T Biotin HLA-B*07:02 SARS-CoV-2 Monomer (RPDTRYVL) | SARS-CoV-2 ORF1ab | 280125 | ||||||||||||
| Flex-T Biotin HLA-A*02:01 SARS-CoV-2 Monomer (LLYDANYFL) | SARS-CoV-2 ORF3a | 280079 | ||||||||||||
| Flex-T Biotin HLA-A*24:02 SARS-CoV-2 Monomer (VYFLQSINF) | SARS-CoV-2 ORF3a | 280119 | ||||||||||||
| Flex-T Biotin HLA-A*02:01 SARS-CoV-2 Monomer (ALNTLVKQL) | SARS-CoV-2 Spike Protein | 280027 | ||||||||||||
| Flex-T Biotin HLA-A*02:01 SARS-CoV-2 Monomer (FIAGLIAIV) | SARS-CoV-2 Spike Protein | 280025 | ||||||||||||
| Flex-T Biotin HLA-A*02:01 SARS-CoV-2 Monomer (LITGRLQSL) | SARS-CoV-2 Spike Protein | 280035 | ||||||||||||
| Flex-T Biotin HLA-A*02:01 SARS-CoV-2 Monomer (NLNESLIDL) | SARS-CoV-2 Spike Protein | 280037 | ||||||||||||
| Flex-T Biotin HLA-A*02:01 SARS-CoV-2 Monomer (RLNEVAKNL) | SARS-CoV-2 Spike Protein | 280039 | ||||||||||||
| Flex-T Biotin HLA-A*02:01 SARS-CoV-2 Monomer (RLQSLQTYV) | SARS-CoV-2 Spike Protein | 280073 | ||||||||||||
| Flex-T Biotin HLA-A*02:01 SARS-CoV-2 Monomer (SIIAYTMSL) | SARS-CoV-2 Spike Protein | 280067 | ||||||||||||
| Flex-T Biotin HLA-A*02:01 SARS-CoV-2 Monomer (VLNDILSRL) | SARS-CoV-2 Spike Protein | 280029 | ||||||||||||
| Flex-T Biotin HLA-A*02:01 SARS-CoV-2 Monomer (VVFLHVTYV) | SARS-CoV-2 Spike Protein | 280031 | ||||||||||||
| Flex-T Biotin HLA-A*02:01 SARS-CoV-2 Monomer (YLQPRTFLL) | SARS-CoV-2 Spike Protein | 280071 | ||||||||||||
| Flex-T Biotin HLA-A*03:01 SARS-CoV-2 Monomer (KCYGVSPTK) | SARS-CoV-2 Spike Protein | 280097 | ||||||||||||
| Flex-T Biotin HLA-A*11:01 SARS-CoV-2 Monomer (KCYGVSPTK) | SARS-CoV-2 Spike Protein | 280099 | ||||||||||||
| Flex-T Biotin HLA-A*24:02 SARS-CoV-2 Monomer (QYIKWPWYI) | SARS-CoV-2 Spike Protein | 280117 | ||||||||||||
| Mouse Class I Biotinylated Monomer Fixed Peptide | ||||||||||||||
| 品名 | Peptide Region | 貨號 | ||||||||||||
| Flex-T Biotin H-2 D(b) Flu Monomer (ASNENMETM) | Flu Nucleocapsid | 280045 | ||||||||||||
| Flex-T Biotin H-2 D(b) Flu Monomer (SSLENFRAYV) | Flu Polymerase Acidic Protein | 280047 | ||||||||||||
| Flex-T Biotin H-2 D(b) HPV16 Monomer (RAHYNIVTF) | HPV16 E7 Protein | 280065 | ||||||||||||
| Flex-T Biotin H-2 D(b) LCMV Monomer (FQPQNGQFI) | LCMV Nucleocapsid | 280041 | ||||||||||||
| Flex-T Biotin H-2 D(b) LCMV Monomer (KAVYNFATC) | LCMV Glycoprotein Polyprotein | 280043 | ||||||||||||
| Flex-T Biotin H-2 K(b) LCMV Monomer (ISHNFCNL) | LCMV Glycoprotein Polyprotein | 280049 | ||||||||||||
| Flex-T Biotin H-2 D(b) PMV Monomer (GAPRNRELF) | PMV Nucleocapsid | 280059 | ||||||||||||
| Flex-T Biotin H-2 K(b) OVA Monomer (SIINFEKL) | Chicken Ovalbumin Model Peptide | 280051 | ||||||||||||
| Flex-T Biotin H-2 K(b) Sendai Monomer (FAPGNYPAL) | Sendai Nucleocapsid | 280055 | ||||||||||||
| Flex-T Biotin H-2 K(b) TRP2 Monomer (SVYDFFVWL) | Tyrosinase Related Protein 2 | 280061 | ||||||||||||
| Flex-T Biotin H-2 K(b) VV Monomer (TSYKFESV) | Vaccinia virus protein B8 precursor | 280053 | ||||||||||||
| Flex-T Biotin H-2 K(d) EGFP Monomer (HYLSTQSAL) | Green Fluorescent Protein | 280057 | ||||||||||||
| Flex-T Biotin H-2 K(d) HIV Monomer (AMQMLKETI) | HIV Gag Protein | 280063 | ||||||||||||
| ELISA Reagents | ||||||||||||||
| 品名 | 規格 | 貨號 | ||||||||||||
| Flex-T HLA Class I ELISA Control | 20 μg | 280301 | ||||||||||||
| LEGEND MAX™ Flex-T Human Class I Peptide Exchange ELISA Kit | 1 Pre-coated Plate | 447207 | ||||||||||||
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